Portfolio News 2008

October 17, 2008
CeNeRx BioPharma initiates Phase 2 clinical trial of its novel antidepressant agent Tyrima™
October 17, 2008
CeNeRx BioPharma completes $15 Million Series B financing
September 23, 2008
Anthera completes special protocol assessment with FDA and receives EMEA scientific advice on development path toward varespladib approval
September 5, 2008
CoLucid presents Phase 2 results of COL-144 at European Headache and Migraine Trust International Congress 2008
September 3, 2008
Plexxikon initiates Phase 1 Trial for PLX5568
August 25, 2008
Anthera advances global development strategy for varespladib with the initiation of FRANCIS trial
July 22, 2008
CeNeRx BioPharma to initiate Phase 2 trials for its novel antidepressant agent Tyrima™ using innovative brain imaging study
July 1, 2008
CoLucid announces $25 million Series B financing for advancement of first-in-class migraine compound
June 25, 2008
Methylgene announces the initiation of a Phase 2 trial of MGCD0103
May 21, 2008
Plexxikon announces preclinical data demonstrating dramatic improvement in key symptoms of polycystic kidney disease
May 20, 2008
Dynogen presents results of its positive Phase 2 IBS-d study with DDP225
April 30, 2008
Genstruct and Sirtris Pharmaceuticals win Bio-IT World's Best Practices Award
April 17, 2008
BrainCells expands Series B financing to $50 million
April 17, 2008
BrainCells Inc. initiates Phase 2 clinical trial with BCI-540 for depression with anxiety
April 16, 2008
MethylGene initiates Phase 1 clinical trial for its multi-targeted (c-Met) kinase inhibitor, MGCD265, in solid tumor cancers
April 16, 2008
Bayhill Therapeutics presents data from a Phase 2 trial of BHT-3009 in multiple sclerosis at American Academy of Neurology 60th annual meeting
April 16, 2008
DSMB supports continuation of Anthera Phase 2 impacts trial for the prevention of acute chest syndrome in patients with sickle cell disease
April 7, 2008
UCSD, TargeGen team-up on blood disease treatment
March 27, 2008
LipoScience: LDL particle measurement by NMR recognized in consensus statement by the ADA and the ACC
March 19, 2008
Genstruct: Patience, Persistence, and Payoff
March 17, 2008
BioSyntech announces positive preliminary interim data for BST-CarGel® clinical trial
March 4, 2008
Biovitrum and Syntonix set to begin Phase 1/2a clinical trial for the treatment of Hemophilia B
February 28, 2008
TyRx Pharma raises $25 million
February 27, 2008
Athersys announces summary results for Phase 1 safety study of its novel obesity drug
February 20, 2008
Genstruct announces new collaboration with Pfizer in drug safety
February 14, 2008
MethylGene and Pharmion announce orphan drug designation for treatment of acute myelogenous leukemia
February 6, 2008
Apex Bioventures and Dynogen Pharmaceuticals announce definitive merger agreement
January 31, 2008
TargeGen announces initiation of clinical trial of JAK2 inhibitor TG101348 in myeloproliferative disease patients
January 31, 2008
Anthera enters into manufacturing agreements for Varespladib in preparation for pivotal Phase 3 trials
January 16, 2008
Dynogen expands DDP225 patent estate
January 15, 2008
Anthera announces preliminary positive results from once-daily A-002 Phase 2 cardiovascular trial
January 9, 2008
Bayhill Therapeutics files registration statement for proposed initial public offering